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Paget's disease of the vulva--a review of our experience
S Petković1, K Jeremić, S Vidakovic
1Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade (Serbia and Montenegro).
Objective:
The aim of our study was to review our experience with Paget's disease of the vulvar relative to initial examination, treatment and oncological outcome.
Methods:
Ten women with extramammary Paget's diseases of the vulva were treated during the 10-year period. The charts of these patients were reviewed and data were collected regarding patient demographics, symptoms, previous Paget's disease, surgical treatments and time to recurrence.
Results:
Eight women (80%) were treated with wide local excision or partial vulvectomy, and two patients (20%) required radical resection for invasive adenocarcinoma. The group of women who had invasive diseases also underwent inquinofemoral lymphadenectomy and no lymphatic metastases were noted. Three women (30%) experienced recurrence. The mean time to relapse was 30 months (range 3-88 months).
Conclusion:
Recurrence is very common and long-term monitoring is recommended with careful examination of any abnormal vulvar lesion.
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