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Updated: Jul 17, 2026

Electrochemical Preparation of Poly(3,4-Ethylenedioxythiophene) Layers on Gold Microelectrodes for Uric Acid-Sensing Applications
Published on: July 28, 2021
First enzymatic synthesis of water-soluble conducting poly(3,4-ethylenedioxythiophene)
Valérie Rumbau1, Jose A Pomposo, Aitziber Eleta
1New Materials Department, CIDETEC--Centre for Electrochemical Technologies, Parque Tecnologico de San Sebastian, Paseo Miramon 196, E-20009 Donostia-San Sebastian, Spain.
Abstract:
The enzymatically catalyzed polymerization of 3,4-ethylenedioxythiophene in the presence of polystyrenesulfonate is introduced. This is the first time that an enzymatically catalyzed poly(3,4-ethylenedioxythiophene) (PEDOT) is reported. Horseradish peroxidase enzyme was used as a catalyst for the polymerization process leading to a water-soluble PEDOT that was characterized by UV-vis spectra, Fourier transform infrared, and electrical conductivity measurements. Water-soluble PEDOT showed excellent film formation ability as confirmed by atomic force microscopy images.

