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Updated: Jul 17, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade

Published on: August 14, 2019

Flavonoids from Limnophila indica.

Nimmanapalli P Reddy¹, Bandi A K Reddy, Duvvuru Gunasekar

¹Natural Products Division, Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India.

|February 13, 2007

Summary

Researchers isolated five flavonoids from the Limnophila indica plant, including two novel compounds. Spectral and chemical analyses confirmed the structures of these important natural products.

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Area of Science:

Phytochemistry
Natural Product Chemistry
Organic Chemistry

Background:

The Limnophila indica plant is a source of bioactive natural products.
Flavonoids are a diverse class of plant secondary metabolites with various biological activities.
Understanding the chemical constituents of medicinal plants is crucial for drug discovery.

Purpose of the Study:

To isolate and characterize flavonoid compounds from the whole plant of Limnophila indica.
To identify novel flavonoid structures and elucidate their chemical properties.

Main Methods:

Phytochemical investigation of Limnophila indica.
Isolation of compounds using chromatographic techniques.
Structure elucidation through comprehensive spectral analysis (NMR, MS) and chemical studies.

Related Experiment Videos

Last Updated: Jul 17, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade

Published on: August 14, 2019

Main Results:

Two novel flavonoids, (2S)-5,7,3',4'-tetramethoxyflavanone (1) and 5,7,2',5'-tetramethoxyflavone (2), were isolated.
Three known flavonoids, 7-O-methylwogonin (3), skullcapflavone I (4), and 5-hydroxy-7,2'-dimethoxyflavone (5), were also identified.
The structures of all five isolated compounds were confirmed via spectral and chemical evidence.

Conclusions:

The phytochemical analysis of Limnophila indica yielded five flavonoids, including two new compounds.
The structural characterization provides valuable data on the chemical diversity of flavonoids from this plant species.
This study contributes to the knowledge of natural products and their potential applications.