Does treatment delay predict occupational functioning in first-episode psychosis?

Area of Science:

• Psychiatry
• Mental Health Research
• Social Psychiatry

Background:

• Duration of untreated psychosis (DUP) is a known predictor of symptom outcomes in first-episode psychosis (FEP).
• Evidence linking DUP to social functioning outcomes, specifically occupational activity, is less established.
• Occupational functioning is a critical aspect of recovery and long-term well-being in individuals with FEP.

Purpose of the Study:

• To investigate the relationship between DUP and occupational activity at three-year follow-up in a cohort of first-episode psychosis patients.
• To examine the role of social support as a potential moderator or mediator in this relationship.
• To provide evidence supporting early intervention and social support strategies for improving occupational outcomes in FEP.

Main Methods:

• Prospective study design involving 163 patients diagnosed with first-episode psychosis.
• Assessment of duration of untreated psychosis (DUP) at baseline.
• Evaluation of occupational activity (full-time) at three-year follow-up.
• Measurement of social support levels during the study period.

Main Results:

• A shorter duration of untreated psychosis (DUP) was significantly associated with increased full-time occupational activity at three years.
• Higher levels of social support were also significantly linked to greater full-time occupational activity at follow-up.
• These associations remained significant after controlling for relevant covariates.

Conclusions:

• Reducing treatment delay (shorter DUP) is crucial for improving long-term occupational outcomes in first-episode psychosis.
• Enhancing social support networks is an important strategy to foster better occupational functioning in this population.
• Integrated approaches addressing both DUP and social support are recommended for comprehensive FEP care.