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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...

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Related Experiment Video

Updated: Jul 17, 2026

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

Rolling back malaria: how well is Europe doing?

Stephen Toovey¹, Andrew Jamieson

¹American Society of Travel Medicine Certified in Clinical Tropical Medicine and Travelers' Health, SAA-Netcare Travel Clinics, P.O. Box 786692, Sandton 2146, South Africa.

Travel Medicine and Infectious Disease

|February 13, 2007

Summary

Europe

Area of Science:

Global Health
Epidemiology
Public Health Policy

Background:

The Roll Back Malaria (RBM) initiative aims to halve the global malaria burden by 2010.
RBM focuses on five critical concepts for malaria control, primarily in developing nations.
Europe, recently free of malaria, faces a continuous threat of reintroduction.

Purpose of the Study:

To assess the threat of imported malaria in Europe.
To evaluate Europe's response to imported malaria against RBM's critical concepts.

Main Methods:

Searched RBM, WHO, European Union (Eurosurveillance), and Medline databases for "imported malaria."
Followed links to related articles and independently assessed citations for relevance.
Benchmarked European response against RBM's critical concepts.

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Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Published on: December 4, 2015

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Published on: July 11, 2025

Related Experiment Videos

Last Updated: Jul 17, 2026

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Published on: December 4, 2015

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Published on: July 11, 2025

Main Results:

Europe's response to imported malaria is only adequate in terms of disease surveillance.
Other RBM critical concepts are not sufficiently addressed in the European context.

Conclusions:

Europe needs to enhance its efforts and strategies to combat imported malaria.
Greater focus on RBM's critical concepts is recommended for effective malaria prevention in Europe.