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Tuberculosis in travellers.

Victoria J Johnston1, Alison D Grant

  • 1Hospital for Tropical Diseases, University College London Hospitals, London, UK.

Travel Medicine and Infectious Disease
|February 13, 2007
PubMed
Summary
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International travel increases tuberculosis (TB) risk, especially for long-term travelers and healthcare workers. Pre-travel assessment and preventive strategies are crucial for mitigating TB infection and disease.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Travel Medicine

Background:

  • Tuberculosis (TB) incidence is rising globally, particularly in popular travel destinations.
  • Active TB development involves infection risk and host immune status.
  • Travelers, especially long-term visitors and healthcare workers, face elevated TB risks.

Purpose of the Study:

  • To assess the risk of TB infection and disease in international travelers.
  • To review current TB prevention strategies for travelers.
  • To highlight the need for pre-travel risk assessment and tailored advice.

Main Methods:

  • Review of TB incidence data in popular travel destinations.
  • Analysis of TB infection and disease risk factors for travelers.

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  • Evaluation of existing TB prevention recommendations for international travelers.
  • Main Results:

    • Holidaymakers have a low TB risk, but long-term travelers may face risks similar to local populations (0.5-2.5% annually).
    • Healthcare workers in high-incidence areas are at particularly high risk.
    • Current prevention strategies, including BCG vaccination and testing, vary and require optimization.

    Conclusions:

    • Effective pre-travel advice must include risk assessment for TB infection and disease.
    • Preventive strategies like avoidance, BCG vaccination, and chemoprophylaxis should be considered based on individual risk.
    • Further research is needed on travel's contribution to TB incidence in industrialized nations.