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Updated: Jul 17, 2026

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method
16:07

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method

Published on: September 16, 2017

Travel in patients receiving TNF-alpha inhibitors

Robert Orenstein1

  • 1Divisions of General Internal Medicine and Infectious Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

Travel Medicine and Infectious Disease
|February 13, 2007
PubMed

The TNF-alpha inhibitors, infliximab (Remicade), etanercept (Enbrel) and adalimumab (Humira) are increasingly being used for chronic inflammatory diseases and have effectively allowed many patients to return to more active lifestyles. The impact of these agents on immune function has led to the recognition of specific infectious complications. The combination of the increasingly active lifestyles of those receiving these agents and their immunosuppressive effects pose new challenges for practitioners of travel medicine. The purpose of this article is to review the immunologic and infectious consequences of these therapies and their potential impact on travelers.

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