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Updated: Jul 17, 2026

Multimodal Study of Murine Cardiovascular Remodeling: Four-Dimensional Ultrasound and Mass Spectrometry Imaging
Published on: January 10, 2025
Proteomics and metabolomics combined in cardiovascular research
Manuel Mayr1, Basetti Madhu, Qingbo Xu
1Cardiovascular Division, King's College, London SE5 9NU, UK. manuel.mayr@kcl.ac.uk
Abstract:
Proteomics and metabolomics offer a nonbiased suite of tools to address pathophysiologic mechanisms from various levels by integrating signal transduction, cellular metabolism, and phenotype analysis. To link alterations of cellular proteins to metabolism and function, we have recently combined proteomic and metabolomic techniques. Examples, including genetic manipulation, ischemic preconditioning, atherosclerosis, and stem cell differentiation, are discussed to illustrate how the combination of these updated technologies may advance our understanding of cardiovascular biology.
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