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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Cardiovascular disease: strategies for risk assessment and modification
1Preventive Cardiology Center; Associate Professor, College of Nursing, Rush University, Chicago, IL 60612, USA. lynne_t_braun@rush.edu
Insights
Silent myocardial ischemia, a condition affecting millions, indicates poor prognosis for cardiovascular disease. Early detection of subclinical coronary atherosclerosis and risk factor modification are crucial for prevention.
Area of Science:
- Cardiology
- Preventive Medicine
- Public Health
Background:
- Cardiovascular disease is the leading cause of death in the US.
- Silent myocardial ischemia affects millions, posing a poor prognosis.
- Subclinical coronary atherosclerosis assessment aids long-term risk identification.
Purpose of the Study:
- To highlight the significance of silent myocardial ischemia.
- To discuss the role of subclinical coronary atherosclerosis in risk assessment.
- To emphasize comprehensive cardiovascular risk factor modification.
Main Methods:
- Review of traditional and novel cardiovascular risk factors.
- Discussion of risk assessment strategies for coronary artery disease.
- Emphasis on guideline-based risk reduction interventions.
Main Results:
- Silent myocardial ischemia is a significant predictor of poor outcomes.
- Novel factors like lipoprotein(a), homocysteine, and CRP enhance risk assessment.
- Risk modification strategies include lifestyle changes and medical management.
Conclusions:
- Early identification of silent myocardial ischemia and subclinical atherosclerosis is vital.
- Aggressive modification of risk factors is essential for primary and secondary prevention.
- Clinician knowledge of national guidelines maximizes cardiovascular risk reduction.
Abstract:
Cardiovascular disease is the leading cause of death among men and women in the United States. Silent myocardial ischemia, defined as documentation of ischemia in the absence of angina or anginal equivalents, affects up to 4 million Americans and carries a poor prognosis. The assessment of the presence of subclinical coronary atherosclerosis affords an opportunity to identify patients who may be at risk for coronary artery disease over the long term. In addition to traditional risk factors (such as lipid parameters, diabetes, hypertension, smoking, and age), a variety of novel factors (such as lipoprotein[a], homocysteine, and C-reactive protein) may enhance assessment of risk in specific populations. Risk modification should be aimed at achieving recommended levels of lipids and blood pressure, reducing obesity, facilitating optimal management of diabetes and the metabolic syndrome, and encouraging smoking cessation and physical activity. Clinicians should be knowledgeable regarding the application of national guidelines for the reduction of cardiovascular risk so as to maximize the prospects for both the primary and secondary prevention of coronary artery disease and associated adverse outcomes.
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