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A common coding variant in CASP8 is associated with breast cancer risk

Angela Cox1, Alison M Dunning, Montserrat Garcia-Closas

  • 1Sheffield University Medical School, Sheffield S10 2RX, UK.

Nature Genetics
|February 13, 2007
PubMed
Summary

The Breast Cancer Association Consortium identified genetic variants in CASP8 and TGFB1 associated with breast cancer risk. This study highlights the power of large-scale genetic analysis in uncovering common susceptibility alleles with small effects.

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