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Published on: July 25, 2025
High accuracy of virtual simulation with the laser system Dorado CT4
Dirk Rades1, Thorsten Frenzel, Rudolf Schwarz
1Department of Radiation Oncology, University Medical Center, Hamburg-Eppendorf, Germany. Rades.Dirk@gmx.net
Summary
Virtual simulation using the Dorado CT4 laser system accurately targets prostate cancer treatment isocenters. Using a 3 mm slice thickness during planning CT scans ensures high precision for radiotherapy.
Area of Science:
- Medical Physics
- Radiation Oncology
- Radiotherapy Planning
Background:
- Virtual simulation offers a time-efficient alternative to physical simulation in radiotherapy.
- Accurate patient positioning is critical for effective radiation delivery in prostate cancer treatment.
Purpose of the Study:
- To assess the accuracy of virtual simulation with the Dorado CT4 laser system for prostate cancer patients.
- To compare virtual simulation accuracy using different CT scan parameters.
Main Methods:
- Virtual simulation was performed on 96 prostate cancer patients.
- Two groups were analyzed: Group A (8 mm slice thickness) and Group B (3 mm slice thickness).
- The maximum difference (Deltamax) between virtual and physical simulation isocenters was evaluated.
Main Results:
- The entire cohort showed a mean Deltamax of 5.7 mm.
- Group B (3 mm slice thickness) demonstrated higher accuracy with a mean Deltamax of 4.8 mm compared to Group A (6.2 mm).
- Radiotherapy type and regimen did not significantly impact Deltamax.
Conclusions:
- Virtual simulation with the Dorado CT4 system is highly precise for prostate cancer radiotherapy.
- A planning CT with 3 mm reconstruction index and 3 mm slice thickness is recommended for optimal accuracy.
- This method is effective for both primary and salvage radiotherapy, including external-beam radiotherapy (EBRT) and high-dose-rate brachytherapy (HDR-BT).
