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Related Experiment Videos

A new technique for bladder washing.

D C Miller1, D L Fitkin, K A Kropp

  • 1Department of Urology, Medical College of Ohio, Toledo 43699.

The Journal of Urology
|January 1, 1992
PubMed
Summary
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Water Pik irrigation significantly increases transitional cell yield in bladder wash specimens compared to traditional methods. This simple adaptation enhances diagnostic accuracy for bladder conditions.

Area of Science:

  • Urology
  • Medical Devices
  • Diagnostic Cytology

Background:

  • Accurate bladder wash specimens are crucial for diagnosing urothelial abnormalities.
  • Traditional methods like syringe barbotage may yield insufficient cellular material.

Purpose of the Study:

  • To evaluate the efficacy of a modified Water Pik device for enhancing cell yield in bladder wash specimens.
  • To compare cell counts obtained with Water Pik irrigation versus conventional techniques.

Main Methods:

  • A modified Water Pik device was used for direct-vision bladder wall agitation in mongrel dogs.
  • Three experimental groups: syringe barbotage, half-speed Water Pik, and full-speed Water Pik irrigation.
  • Transitional cell counts were performed on centrifuged bladder wash specimens.

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Main Results:

  • Syringe barbotage yielded cell counts similar to controls.
  • Both half-speed (5.7 cells/hpf) and full-speed (13.7 cells/hpf) Water Pik irrigation resulted in statistically significant increases in transitional cell counts.
  • Full-speed Water Pik irrigation demonstrated the highest cell yield.

Conclusions:

  • Water Pik irrigation is an effective and simple method to increase cell yield in bladder wash specimens.
  • This technique holds potential for improving the diagnostic sensitivity of urine cytology.
  • Further studies are warranted to validate this method in human subjects.