EEG-fMRI in children with pharmacoresistant focal epilepsy
Xavier De Tiège1, Helmut Laufs, Stewart G Boyd
1Neuroscience Unit, UCL Institute of Child Health, London, United Kingdom. xdetiege@ulb.ac.be
Purpose:
To evaluate the usefulness of EEG-combined functional magnetic resonance imaging (EEG-fMRI) to localize epileptogenic sources.
Methods:
Six children (age 8-15 years) with lesional or nonlesional pharmacoresistant focal epilepsy were studied.
Results:
We found significant activations in four children, activation and deactivation in one child, and widespread deactivation in another. In four children, activations colocalized with the presumed location of the epileptic focus, one of which was confirmed by intracranial EEG.
Conclusions:
EEG-fMRI is a promising tool to noninvasively localize epileptogenic regions in children with pharmacoresistant focal epilepsy.
More Related Videos
10:23Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy
Published on: June 23, 2023
09:57Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
