Related Experiment Video
Updated: Jul 17, 2026

Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography
Published on: November 24, 2016
[The electrocardiogram in acute myocardial infarction with reperfusion: current concepts regarding Q waves and their
1Klinika kardiologie IKEM, Praha. jan.sochman@medicon.cz
Abstract:
The formation of Q waves in patients with myocardial infarction with primary ECG - documented ST elevations has been the subject of considerable attention. Less widely known, however, has been the fact that Q waves need not be a permanent feature and may disappear or decrease in quantity in some patients. For some time, the Q wave was perceived as a transmural extent of predominantly non-viable myocardial structures (scars or fibrosis). A most effective method for infarct-related artery recanalization is now available and the latest techniques have demonstrated beyond any doubt that even an invariable Q wave need not necessarily indicate loss of myocardial viability. Even in the era of thrombolysis, successful recanalization of an infarctrelated artery led to a specific ECG pattern in patients undergoing artery recanalization or reperfusion of the corresponding myocardial segment. The main features included a decrease in Q waves and, possibly, an increase in R waves in the ECG leads reflecting the respective ischemic events. This overview provides evidence of the significance of the Q wave in the ECG. It therefore comes as a surprise that modern cardiology has given so little attention to the above facts.
Related Concept Videos
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin to...
Cardiac Action Potential
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
ECG Interpretation of Rhythms
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage. When...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

