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Updated: Jul 17, 2026
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Giant cell arteritis with spontaneous remission
1Midwest Eye Institute, and Indiana University Medical Center, Department of Ophthalmology, Indianapolis, Indiana 46280, USA. vpurvin@iupui.edu
Background:
Clinical manifestations of giant cell arteritis (GCA) are variable. Whether signs and symptoms present in an explosive fashion or insidiously, once manifest the course is usually progressive unless treatment is initiated.
Methods:
A retrospective review of patients with GCA seen in an outpatient neuro-ophthalmology clinic.
Results:
We report four patients with biopsy-proven GCA who experienced spontaneous remission. Clinical manifestations consisted of headache and diplopia in two patients, constitutional symptoms in one patient and facial pain in another.
Conclusions:
Clinicians should be aware of this aspect of the disease in order to avoid a delay in diagnosis and treatment.
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