Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Accessory Structures of the Skin: Nails

Accessory Structures of the Skin: Nails

Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...

Changes in Skin Color: Clinical Perspectives

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Dilated Pore of Winer on the Thigh: Clinical and Histopathological Correlation.

Cureus·2025

Same author

Secondary syphilis.

Journal of the American Academy of Dermatology·2025

Same author

Successful Treatment of Cutaneous Larva Migrans With Combined Albendazole and Ivermectin Therapy: A Report of Two Cases From Sudan.

Cureus·2024

Same author

Oral Lichen Planus: An Updated Review of Etiopathogenesis, Clinical Presentation, and Management.

Indian dermatology online journal·2024

Same author

Intravascular Papillary Endothelial Hyperplasia Involving the Hand: A Case Report of a Rare Entity.

Cureus·2024

Same author

Topical Therapy in Psoriasis.

Indian journal of dermatology·2023

Search research articles

Related Experiment Video

Updated: Jul 17, 2026

Measuring Psoriasis Severity at Home

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Nail changes in childhood psoriasis: a study from Kuwait.

Nawaf Al-Mutairi¹, Yashpal Manchanda, Osama Nour-Eldin

¹Department of Dermatology and Venereology, Farwaniya Hospital, Farwaniya 80000, Kuwait. nalmut@usa.net

Pediatric Dermatology

|February 16, 2007

Summary

Nail changes affect over a third of children with psoriasis, with nail pitting being the most common issue. These findings are important for understanding childhood psoriasis and its impact on nails.

Related Experiment Videos

Last Updated: Jul 17, 2026

Measuring Psoriasis Severity at Home

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

Dermatology
Pediatrics
Clinical Medicine

Background:

Psoriasis is a common skin condition affecting many individuals.
Nail involvement in psoriasis is frequent, but data on childhood cases are limited.

Purpose of the Study:

To determine the frequency and types of nail changes in children with psoriasis.
To compare findings with existing literature on childhood psoriasis nail involvement.

Main Methods:

A study was conducted on 201 new pediatric psoriasis patients (age ≤ 16).
Clinical dermatologic examinations focused on nail changes.
Mycologic investigations were performed if fungal infection was suspected.

Main Results:

Nail changes were observed in 37.81% of pediatric psoriasis patients, with boys affected more than girls.
The most common nail changes included pitting (61.84%), onycholysis (30.26%), and subungual hyperkeratosis (13.16%).
Nail involvement showed no correlation with psoriasis type, sex, duration, or extent of disease.

Conclusions:

Nail abnormalities are a significant feature of childhood psoriasis.
Nail pitting is the predominant manifestation in this age group.