Related Experiment Video
Updated: Jul 17, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Onychomatricoma: first description in a child
Bianca Maria Piraccini1, Angela Antonucci, Giulia Rech
1Department of Dermatology, University of Bologna, St. Orsola-Malpighi Hospital, Via Massarenti 1, 40138 Bologna, Italy. bmpiracc@med.unibo.it
Onychomatricoma, a rare nail matrix tumor, presents unique signs like ridging and discoloration. This case highlights its co-occurrence with onychomycosis in a young child.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Onychomatricoma is a rare, benign neoplasm originating from the nail matrix.
- It exhibits distinct clinical, histological, and ultrastructural characteristics.
Observation:
- The study details a rare case of onychomatricoma in a 4-year-old girl.
- This specific case also presented with coexisting onychomycosis in the affected nail.
Findings:
- Onychomatricoma typically manifests with longitudinal ridging, yellow nail discoloration, splinter hemorrhages, and nail overcurvature.
- The association of onychomatricoma with onychomycosis in the same nail is an unusual finding.
Implications:
- This case expands the understanding of onychomatricoma's clinical presentation, particularly in pediatric patients.
- Recognizing this dual pathology is crucial for accurate diagnosis and appropriate management of nail disorders.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Bone Formation by Endochondral Ossification
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
