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Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
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Pediatric HIV Infection

Teresa Espanol1, Isabel Caragol, Pere Soler

  • 1Department of Immunology and Immunodeficiencies, Hospital Vall d´Hebron, School of Medicine, Barcelona, Spain. tespanol@vhebron.net.

Iranian Journal of Allergy, Asthma, and Immunology
|February 16, 2007
PubMed

HIV infection by maternal transmission is increasing in the world due to the increase in infected women who are not receiving appropriate antiretroviral therapy. Prognosis of HIV infection in children is poor because the newborn has an immature immune system. Early diagnosis and therapy are needed to avoid the development of AIDS. New therapies are becoming available but prevention of infection, through maternal therapy during pregnancy, is the most effective measure in avoiding this infection through this transmission route.

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