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Updated: Jul 16, 2026
10:52
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
[Malignant lymphoma]
1Dept. of Strategic Medicine, Division of Pediatric Oncology, National Center for Child Health and Development.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|February 16, 2007
Summary
Standard chemotherapy offers over 70% survival for pediatric non-Hodgkin lymphoma. Recent treatment advances for childhood non-Hodgkin lymphoma subtypes are highlighted, based on clinical trial data.
Area of Science:
- Pediatric Oncology
- Hematology
- Clinical Trials
Context:
- Childhood non-Hodgkin lymphoma (NHL) treatment has seen significant progress.
- Survival rates for pediatric NHL have improved substantially over recent decades.
Purpose:
- To review advances in treatment for pediatric non-Hodgkin lymphoma.
- To focus on clinical trial results from European and North American study groups for each NHL subtype.
Summary:
- Standard chemotherapy achieves over 70% 5-year survival in children and adolescents with non-Hodgkin lymphoma.
- The report details treatment improvements across various pediatric NHL histologic subtypes.
- Key findings are derived from published clinical trial outcomes.
Impact:
- Improved understanding of current pediatric non-Hodgkin lymphoma treatment efficacy.
- Provides a basis for future research and therapeutic strategies in pediatric oncology.
- Highlights the success of collaborative multi-center clinical trials in advancing cancer care.
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