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Published on: August 14, 2019

[Differences in the risk factors for clinical benign prostatic hyperplasia between the Mongolian and the Han people]

Yun-bin Wang1, Li-ping Xie, Ya-guang Yuan

  • 1Department of Urology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China. wangyunb@163.com

Zhonghua Nan Ke Xue = National Journal of Andrology
|February 17, 2007
PubMed

Insights

Mongolian men with benign prostatic hyperplasia (BPH) show higher rates of alcohol consumption, a protein-rich diet, and intraprostatic inflammation compared to Han men. Smoking also correlates with surgical treatment for BPH in Mongolians.

Area of Science:

  • Urology
  • Epidemiology
  • Men's Health

Background:

  • Benign prostatic hyperplasia (BPH) is a common condition affecting aging men.
  • Risk factors for BPH can vary significantly across different ethnic populations.
  • Understanding these differences is crucial for targeted prevention and treatment strategies.

Purpose of the Study:

  • To investigate and define the distinct risk factors associated with clinical benign prostatic hyperplasia (BPH) in Mongolian versus Han populations.
  • To identify potential etiological differences that may explain variations in BPH prevalence or severity between these two ethnic groups.

Main Methods:

  • A comparative study involving 126 patients (63 Mongolian, 63 Han) diagnosed with BPH.
  • Data collection utilized a structured questionnaire focusing on known and potential BPH risk factors.
  • Interviews were conducted between January 2003 and June 2005.

Main Results:

  • Mongolian patients reported significantly higher intake of alcohol, dairy products, and meat compared to Han patients.
  • A greater proportion of Mongolian patients were smokers with moderate to severe BPH symptoms (IPSS > 7).
  • Higher incidences of intraprostatic chronic inflammation and prostatic calcification were observed in the Mongolian group.

Conclusions:

  • Mongolian BPH patients exhibit a distinct risk factor profile, including greater alcohol consumption, a higher protein diet, and increased intraprostatic inflammation compared to Han patients.
  • Smoking (smoking index >300) was identified as a factor more likely to lead to surgical intervention in Mongolian BPH patients.
  • These findings highlight ethnic-specific risk factors for BPH, suggesting potential differences in disease pathogenesis or environmental influences.
Abstract

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