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Updated: Jul 16, 2026
The Efficacy and Underlying Pathway Mechanisms of ShiDuGao Treatment for Anus Eczema Based on GEO Datasets and Network Pharmacology
Published on: January 12, 2024
[Clinical study on treatment of acute eczema by Shuangfujin]
Yan-ping Bai1, Ding-quan Yang, Yu-ming Wang
1Department of Dermatology, China-Japan Friendship Hospital, Beijing. byppas601@sina.com.cm
Objective:
To evaluate the effects and safety of Shuangfujin (SFJ) on acute eczema.
Methods:
One hundred and twenty patients with acute eczema were randomly assigned to 4 groups equally, the saline group, the boric acid group, the Pifukang lotion group and the SFJ group, treated with respective medicine.
Results:
After 4 days of treatment, the symptom score was remarkably lower in the SFJ group than in the other three groups (P<0.01), score in the saline group was higher than that in the boric acid group and the Pifukang lotion group, and insignificant difference was shown between the latter two groups. The total effective rate and cured rate were 46.4% and 14.3% in the SFJ group, which were matched to those in the Pifukang lotion group and significantly higher than those in the other two groups (P <0.01), and the saline group showed the lowest efficacy. The effect of stopping itch in the SFJ and the boric acid group were matched, which was higher than that in the Pifukang lotion group, and the lowest was in the saline group. No skin irritant reaction and other adverse reactions were found.
Conclusion:
SFJ is effective, safe and convenient in treating acute eczema.