Related Experiment Video
Updated: Jul 16, 2026

Primary Culture of Porcine Retinal Pigment Epithelial Cells
Published on: September 23, 2022
An insertion/deletion in the porcine FGFR2 gene
J Aldenhoven1, A Spötter, O Distl
1Centre for Advanced Technologies in Animal Genetics and Reproduction (Reprogen), Faculty of Veterinary Science, University of Sydney, NSW, Australia.
Abstract:
The 7000-rad INRA-University of Minnesota porcine Radiation Hybrid panel was used to localize the FGFR2 gene on Sus scrofa chromosome 14 (SSC14). An insertion/deletion mutation of approximately 240 bp was detected in the porcine FGFR2 gene. This mutation consists of a repeat motif of 48 bp. In a short and long variant of this polymorphism, the motif was repeated either six or 11 times. The mutation was shown to follow a Mendelian mode of inheritance in 10 families including 48 pigs of Large White x Duroc origin.
Related Concept Videos
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...
In-vitro Mutagenesis
Point and Frameshift Mutations
