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Updated: Jan 19, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
One-year mean follow-up of 41 patients treated with bifurcation stenting
Nauman Naseer1, Raja Varma, Wilbert S Aronow
1Cardiology Division, Department of Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY 10595, USA.
Insights
Coronary artery stenting of bifurcation lesions showed favorable outcomes, with low rates of major adverse cardiac events including myocardial infarction and restenosis after 12 months. Crushing stent technique was most commonly used.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Biomedical Engineering
Background:
- Bifurcation coronary artery lesions present unique challenges for percutaneous coronary intervention.
- Optimal stent deployment strategies are crucial to minimize adverse events in these complex anatomies.
Purpose of the Study:
- To evaluate the safety and efficacy of various stenting techniques for bifurcation coronary artery lesions.
- To assess the mid-term clinical outcomes following stent implantation in this patient cohort.
Main Methods:
- Retrospective analysis of 41 patients undergoing stenting for bifurcation coronary artery lesions.
- Utilized techniques included crushing stent (80%), T stent (15%), kissing stent (2%), and side branch angioplasty (2%).
- Mean follow-up duration was 12 months.
Main Results:
- No deaths occurred during the follow-up period.
- Low incidence of major adverse cardiac events: 2% myocardial infarction, 7% stent occlusion, 7% restenosis, and 10% target lesion revascularization.
- Overall, 15% experienced myocardial infarction, target lesion revascularization, or death.
Conclusions:
- Stenting of bifurcation coronary artery lesions, particularly with the crushing technique, demonstrates acceptable safety and efficacy.
- The study suggests favorable mid-term outcomes with low rates of major adverse cardiac events in patients treated for bifurcation lesions.
Abstract:
Forty-one patients, mean age 61 +/- 13 years, had stenting of bifurcation coronary artery lesions. Of the 41 patients, a crushing stent was used in 33 patients (80%), a T stent in 6 patients (15%), a kissing stent in 1 patient (2%), and side branch angioplasty in 1 patient (2%). Mean follow-up was 12 months (range 7-17 months). At follow-up, of the 41 patients, none (0%) died, 1 (2%) had a myocardial infarction, 3 (7%) had thrombotic stent occlusion, 3 (7%) had restenosis, 4 (10%) had target lesion revascularization, and 6 (15%) had myocardial infarction or target lesion revascularization or had died.
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