Mobile cauda equina schwannomas
E A Marin-Sanabria1, I M Sih, K K Tan
1Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433.
Singapore Medical Journal
|February 17, 2007
Abstract:
Although very rare, cases of cauda equina tumours migrating several levels have been known to occur. We report two cases of cauda equina schwannomas which migrated from its primary site, one caudally and the other one rostrally as confirmed by magnetic resonance imaging perioperatively. The first patient was a 27-year-old man and the second a 41-year-old man; both presented with back pain. This report aims to remind clinicians that certain tumours attached to the roots in the lumbar spinal canal may migrate.
Related Concept Videos
01:15Spinal Cord: Gross Anatomy
The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
01:25Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...