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Transient splenial lesions in children with "benign convulsions with gastroenteritis"

Jun Natsume1, Misako Naiki, Taro Yokotsuka

  • 1Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan. junnatsu@med.nagoya-u.ac.jp

Brain & Development
|February 20, 2007
PubMed

Insights

Benign convulsions with mild gastroenteritis (CwG) seizures can show temporary abnormalities on MRI diffusion-weighted imaging (DWI) in the corpus callosum splenium. This finding helps differentiate CwG from more serious conditions like encephalitis.

Area of Science:

  • Neurology
  • Pediatric Neurology
  • Neuroradiology

Background:

  • Benign convulsions with mild gastroenteritis (CwG) is a common, benign type of situation-related seizure in children.
  • Typically, neuroimaging in CwG cases reveals no significant abnormalities, aiding in its diagnosis and differentiation from other neurological conditions.

Observation:

  • This study reports on two pediatric patients diagnosed with CwG.
  • Unusual findings were observed on MRI diffusion-weighted imaging (DWI), specifically transient abnormalities in the splenium of the corpus callosum.

Findings:

  • Diffusion-weighted imaging (DWI) revealed temporary abnormalities in the splenium of the corpus callosum in both patients with CwG.
  • These splenial abnormalities were transient, suggesting they are not indicative of permanent structural damage.

Implications:

  • The findings highlight the potential for transient splenial abnormalities on DWI in CwG, which could be mistaken for more severe pathologies.
  • It is crucial to differentiate CwG from conditions like viral encephalitis or encephalopathy, even with these imaging findings.
  • Frequent seizures in CwG might be the cause of these transient DWI abnormalities, emphasizing the need for careful clinical correlation.

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