Related Experiment Video
Updated: Jul 16, 2026
06:27
Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Delayed cord clamping in preterm infants delivered at 34 36 weeks' gestation: a randomised controlled trial
C A Ultee1, J van der Deure, J Swart
1Department of Paediatrics, Deventer Hospital, Deventer, The Netherlands. ulteec@dz.nl
Archives of Disease in Childhood. Fetal and Neonatal Edition
|February 20, 2007
Summary
Delayed umbilical cord clamping in premature infants improves iron status and haemoglobin levels. This practice is linked to better vascular stability and fewer transfusions, supporting long-term infant health.
Area of Science:
- Neonatal Medicine
- Pediatric Hematology
- Perinatal Research
Background:
- Infant iron deficiency and anemia can lead to cognitive deficits.
- Delayed umbilical cord clamping (UCC) enhances hematocrit and vascular stability.
- Previous studies lacked follow-up hemoglobin data post-neonatal period.
Purpose of the Study:
- To evaluate the effects of early versus delayed umbilical cord clamping.
- To provide neonatal and follow-up data on infant iron status.
- To assess the impact of cord clamping timing on premature infants.
Main Methods:
- Randomized controlled trial involving 37 premature infants (34-36 weeks gestation).
- Groups: immediate cord clamping (within 30 seconds) vs. delayed clamping (3 minutes).
- Measurements included blood glucose, hemoglobin, and ferritin levels at birth and 10 weeks.
Main Results:
- Delayed clamping group showed higher hemoglobin levels at 1 hour and 10 weeks.
- Late cord clamping did not correlate with increased jaundice or polycythemia.
- Consistent improvements in iron status were observed with delayed clamping.
Conclusions:
- Immediate umbilical cord clamping should be avoided in premature infants.
- Delayed cord clamping is a safe and effective method to improve infant iron status.
- This practice supports better long-term hematological health outcomes.
