Related Experiment Video

Updated: Jul 16, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Intraperitoneal pressure in PD patients: relationship to intraperitoneal volume, body size and PD-related

Agnès Dejardin1, Annie Robert, Eric Goffin

  • 1Department of Nephrology, Université catholique de Louvain, Brussels, Belgium.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
|February 20, 2007
PubMed

Insights

Intraperitoneal pressure (IPP) in peritoneal dialysis (PD) patients correlates with intraperitoneal volume and body mass index. Higher night IPP is linked to increased enteric peritonitis risk, suggesting IPP measurement guides PD fluid prescription.

Area of Science:

  • Nephrology
  • Gastroenterology
  • Clinical Medicine

Background:

  • Intraperitoneal pressure (IPP) determinants and its impact on peritoneal dialysis (PD) complications are not well understood.
  • This study investigates IPP in new PD patients to identify its clinical determinants and analyze PD-related complications.

Purpose of the Study:

  • To measure IPP in newly started PD patients.
  • To assess the clinical determinants of IPP.
  • To analyze the incidence of PD-related complications in relation to IPP.

Main Methods:

  • IPP was measured in 61 PD patients using varying dialysate volumes.
  • Clinical characteristics and subsequent complications (hernias, leakage, GOR, EP) were assessed.
  • Correlations and survival analyses were performed to evaluate IPP's influence.

Main Results:

  • A strong linear correlation was found between IPP and intraperitoneal volume (IPV).
  • Higher body mass index (BMI) significantly correlated with higher IPP.
  • Elevated night IPP (>14 cm H2O) was associated with a higher incidence of enteric peritonitis (EP) and worse EP-free survival.

Conclusions:

  • IPP is strongly correlated with IPV and significantly influenced by BMI.
  • Higher IPP, particularly at night, increases the risk of enteric peritonitis.
  • Measuring IPP is recommended to optimize PD fluid prescription and potentially reduce complications.
Abstract

More Related Videos

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
Pressure Relationships in Thoracic Cavity01:24

Pressure Relationships in Thoracic Cavity

Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs during...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Pulmonary Ventilation: Inhalation01:24

Pulmonary Ventilation: Inhalation

Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...