Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stereoisomerism02:52

Stereoisomerism

11.1K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
11.1K
Aromatic Hydrocarbon Cations: Structural Overview01:18

Aromatic Hydrocarbon Cations: Structural Overview

3.5K
Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative whole-body dynamic planar scintigraphy in mice with <sup>99m</sup>Tc and <sup>161</sup>Tb.

EJNMMI physics·2025
Same author

Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size.

Pharmaceutics·2024
Same author

Combining Nuclear Medicine With Other Modalities: Future Prospect for Multimodality Imaging.

Molecular imaging·2024
Same author

Optimised production of technetium-94m for PET imaging by proton-irradiation of phosphomolybdic acid in cyclotron liquid target.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2024
Same author

<i>trans</i>-IV restriction: a new configuration for metal bis-cyclam complexes as potent CXCR4 inhibitors.

Dalton transactions (Cambridge, England : 2003)·2024
Same author

In vivo validation of <sup>68</sup>Ga-labeled AMD3100 conjugates for PET imaging of CXCR4.

Nuclear medicine and biology·2023

Related Experiment Video

Updated: May 2, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

9.3K

Copper(II) cyclam-based complexes for radiopharmaceutical applications: synthesis and structural analysis.

Jon D Silversides1, Cheryll C Allan, Stephen J Archibald

  • 1Department of Chemistry and Institute of Clinical Biosciences, The University of Hull, Cottingham Road, Hull, HU6 7RX, UK.

Dalton Transactions (Cambridge, England : 2003)
|February 20, 2007
PubMed
Summary

Structural analysis of copper(II) complexes reveals unusual Jahn-Teller distortions. Novel chelators show pendant arms binding to the metal center, offering new insights into copper coordination chemistry.

More Related Videos

An Optimized Protocol for the Efficient Radiolabeling of Gold Nanoparticles by Using a 125I-labeled Azide Prosthetic Group
07:23

An Optimized Protocol for the Efficient Radiolabeling of Gold Nanoparticles by Using a 125I-labeled Azide Prosthetic Group

Published on: October 10, 2016

7.4K
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
09:12

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

8.8K

Related Experiment Videos

Last Updated: May 2, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

9.3K
An Optimized Protocol for the Efficient Radiolabeling of Gold Nanoparticles by Using a 125I-labeled Azide Prosthetic Group
07:23

An Optimized Protocol for the Efficient Radiolabeling of Gold Nanoparticles by Using a 125I-labeled Azide Prosthetic Group

Published on: October 10, 2016

7.4K
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
09:12

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

8.8K

Area of Science:

  • Coordination Chemistry
  • Crystallography
  • Materials Science

Background:

  • Copper(II) complexes exhibit Jahn-Teller distortion, influencing their molecular structure.
  • The macrocyclic ligand cyclam is commonly used in copper(II) complex studies.
  • Understanding distortion modes is crucial for predicting complex properties.

Purpose of the Study:

  • To determine the molecular structures of two copper(II) complexes, Cu(H(2)TETA).
  • To investigate Jahn-Teller distortion patterns in these complexes.
  • To explore novel chelators based on piperazino/side-bridged cyclam for copper(II) complexation.

Main Methods:

  • X-ray crystallography was employed to determine the molecular structures of two copper(II) complexes.
  • Analysis of over one hundred copper(II) cyclam X-ray structures from the Cambridge Structural Database (CSD).
  • Synthesis and characterization of novel chelators and their copper(II) complexes.

Main Results:

  • Two distinct molecular structures of Cu(H(2)TETA) were identified, showing different Jahn-Teller distortion modes.
  • Jahn-Teller distortion across the macrocyclic ring was found to be highly unusual in copper(II) cyclam complexes.
  • Novel piperazino/side-bridged cyclam chelators formed copper(II) complexes where pendant arms bound to the metal center.

Conclusions:

  • The study highlights diverse Jahn-Teller distortion behaviors in copper(II) complexes.
  • Novel chelator design enables specific coordination geometries and metal binding.
  • Findings contribute to the understanding of copper coordination chemistry and potential applications.