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Related Experiment Videos

Recurrence after total thyroidectomy for benign multinodular goiter.

Kylie L Snook1, Peter L H Stalberg, Stan B Sidhu

  • 1Department of Endocrine and Oncology Surgery, University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, St Leonards, 2065, Sydney, NSW, Australia.

World Journal of Surgery
|February 20, 2007
PubMed
Summary
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Total thyroidectomy for benign multinodular goiter (BMNG) is effective in preventing recurrence. Recurrences are primarily due to failure to remove embryological remnants, not true local regrowth.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Thyroid Surgery

Background:

  • Total thyroidectomy is the standard surgical approach for benign multinodular goiter (BMNG).
  • Recurrent disease after total thyroidectomy for BMNG is unexpected and warrants investigation.

Purpose of the Study:

  • To evaluate the effectiveness of total thyroidectomy in managing BMNG.
  • To identify the underlying causes of recurrent BMNG after complete thyroid removal.

Main Methods:

  • Retrospective analysis of patients undergoing total or secondary total thyroidectomy for BMNG between 1980 and 2005.
  • Identification of patients who developed recurrent BMNG requiring reoperation.

Main Results:

  • Out of 3,044 procedures, 10 patients (0.3%) experienced recurrent BMNG.

Related Experiment Videos

  • Most recurrences (9/11) were linked to embryological remnants (pyramidal and thyrothymic tracts).
  • Only one recurrence was a true local recurrence in the thyroid bed; no complications were noted.

    • Conclusions:

    • Total thyroidectomy is a safe and effective procedure for BMNG, significantly reducing recurrence rates.
    • Failure to excise embryological thyroid remnants is the primary cause of post-thyroidectomy BMNG recurrence.