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Xanthogranulomatous cystitis.

Rajiv Goel1, Gaurang Kadam, Amit Devra

  • 1Department of Urology, Institute of Kidney Diseases and Research Centre, Civil Hospital Campus, 380016, Ahmedabad, Gujarat, India. rajivkanu@rediffmail.com

International Urology and Nephrology
|February 20, 2007
PubMed
Summary
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Xanthogranulomatous cystitis (XC) is a rare bladder condition. Long-term antibiotics and augmentation cystoplasty effectively managed a patient with XC, who remained asymptomatic a year later.

Area of Science:

  • Urology
  • Pathology

Background:

  • Xanthogranulomatous cystitis (XC) is an uncommon, benign, chronic inflammatory bladder condition with an unknown cause.
  • Diagnosis often involves cystoscopy and biopsy, revealing characteristic histological findings.

Observation:

  • A 50-year-old male presented with urgency, frequency, hematuria, and lower abdominal pain.
  • Investigations indicated a small bladder capacity with diverticula.
  • Cystoscopy revealed bladder inflammation and multiple small polypoidal growths.

Findings:

  • Histological examination of biopsies confirmed Xanthogranulomatous cystitis.
  • The patient underwent augmentation cystoplasty and received prolonged broad-spectrum antibiotic therapy.
  • The postoperative period was uneventful, with the patient remaining asymptomatic at one year.

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Implications:

  • This case highlights augmentation cystoplasty and long-term antibiotics as a viable management strategy for Xanthogranulomatous cystitis.
  • Long-term broad-spectrum antibiotics may be considered as a therapeutic trial for patients diagnosed with XC.
  • Further research into the etiology and optimal treatment of XC is warranted.