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Published on: September 20, 2018
Bilateral severe progressive idiopathic lipid keratopathy
Jaime Levy1, Daniel Benharroch, Tova Lifshitz
1Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, 84101, Beer-Sheva, Israel, ljaime@bgu.ac.il
International Ophthalmology
|February 20, 2007
Summary
A rare case of progressive lipid keratopathy occurred in a healthy individual without underlying conditions. This condition, affecting both eyes, required corneal transplantation and careful monitoring for graft rejection.
Area of Science:
- Ophthalmology
- Corneal Diseases
Background:
- Lipid keratopathy is a rare corneal condition.
- Its occurrence in healthy individuals without systemic pathology is unusual.
Observation:
- A 44-year-old healthy male presented with bilateral progressive lipid keratopathy.
- No evidence of hyperlipidemia or corneal neovascularization was initially observed.
Findings:
- Histochemical analysis of corneal buttons revealed lipid deposits and focal stromal vascularization.
- Penetrating keratoplasty (PKP) was performed on both eyes.
- Both corneal grafts experienced rejection episodes, successfully managed with systemic steroids.
Implications:
- Severe lipid keratopathy can develop in healthy corneas without apparent underlying causes.
- The etiology of this condition remains to be elucidated.
- Patients undergoing PKP for lipid keratopathy with identified neovascularization require vigilant post-operative monitoring for graft survival due to increased rejection risk.
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