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Updated: Jul 16, 2026

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules
Published on: August 25, 2009
Supramolecular hydrophobic-hydrophilic nanopatterns at electrified interfaces
Andrey S Klymchenko1, Shuhei Furukawa, Klaus Müllen
1Department of Chemistry, Laboratory of Photochemistry and Spectroscopy, and INPAC - Institute of Nanoscale Physics and Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200-F, 3001 Leuven, Belgium.
Abstract:
We have developed hydrophobic-hydrophilic nanopatterns at electrified surfaces via the self-assembly of amphiphilic molecules. For this purpose, we selected 5-hexadecyloxy isophthalic acid: this neutral amphiphile forms hydrogen-bonded rows that are commensurate with the Au(111) surface. The alkyl chains are interdigitated. The molecular organization of these nanopatterns depends strongly on the substrate potential, which reveals the hierarchical nature of the assembly. The new hydrophobic-hydrophilic nanopatterns are of special interest as templates for the formation of nanostructures of higher complexity.
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