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Related Concept Videos

Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

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Related Experiment Videos

Algorithm for complementary and alternative medicine practice and research in type 2 diabetes.

Ryan Bradley1, Erica B Oberg, Carlo Calabrese

  • 1Bastyr University, Kenmore, WA 98028, USA. rbradley@bastyr.edu

Journal of Alternative and Complementary Medicine (New York, N.Y.)
|February 21, 2007
PubMed
Summary

This study developed clinical algorithms to guide the use of nutritional and botanical medicines for type 2 diabetes management. These models aid in personalized treatment and future research for complementary medicine in diabetes care.

Related Experiment Videos

Area of Science:

  • Integrative Medicine
  • Nutritional Science
  • Pharmacology

Background:

  • Type 2 diabetes management often involves conventional therapies.
  • Nutritional and botanical medicines show potential in improving glycemic control and insulin sensitivity.
  • A structured approach is needed to integrate these complementary therapies into clinical practice.

Purpose of the Study:

  • To develop a clinical model for prescribing nutritional and botanical medicines in type 2 diabetes.
  • To provide a framework for both clinical application and research investigation.
  • To guide the use of supplements based on validated laboratory measures.

Main Methods:

  • Systematic literature review of nutritional and botanical agents.
  • Categorization of agents by mechanism: antioxidant/anti-inflammatory, insulin sensitizer, beta-cell protectant/secretagogue.
  • Development of a clinical decision tree integrating laboratory assessments (glycemic control, insulin resistance, beta-cell reserve).

Main Results:

  • Clinical algorithms were created to direct the use of specific supplements.
  • Evidence-supported nutrients include coenzyme Q10, alpha-lipoic acid, vitamin D, chromium, and omega-3 fatty acids.
  • Botanical medicines like cinnamon, fenugreek, and gymnema were identified with supporting research.

Conclusions:

  • Clinical algorithms can guide the prescription of nutritional and botanical medicines for type 2 diabetes.
  • These algorithms serve as research models for future clinical trials.
  • Further research funding is crucial for evaluating complementary medicine's role in diabetes care and patient safety.