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Outcome of children born out of pregnancies complicated by unexplained polyhydramnios

C Touboul1, P Boileau, O Picone

  • 1Department of Obstetrics and Gynecology, Univ Paris-Sud, Hôpital Antoine Beclè, Clamart, France.

BJOG : an International Journal of Obstetrics and Gynaecology
|February 21, 2007
PubMed

Insights

Unexplained polyhydramnios in pregnancy can lead to serious infant health issues, including West syndrome and pulmonary stenosis. Systematic pediatric follow-up is crucial for affected newborns.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatology
  • Pediatric Neurology

Background:

  • Polyhydramnios, excess amniotic fluid, complicates pregnancies.
  • Unexplained polyhydramnios lacks a clear prenatal cause.
  • Long-term infant outcomes require further investigation.

Purpose of the Study:

  • To evaluate the long-term health outcomes of infants born after pregnancies complicated by unexplained polyhydramnios.
  • To determine the necessity of systematic pediatric follow-up for these infants.

Main Methods:

  • Retrospective analysis of 173 singleton pregnancies with polyhydramnios.
  • Focus on a cohort of 24 infants with unexplained polyhydramnios (negative prenatal testing).
  • Paediatric examination at a median age of 12 months (range 12-64 months).

Main Results:

  • 19 out of 24 infants (79%) had a normal long-term outcome.
  • Three children were diagnosed with West syndrome, polyuria, and pulmonary stenosis.
  • Two perinatal deaths occurred within the cohort.

Conclusions:

  • While most infants have normal outcomes, significant developmental and health issues can arise.
  • Systematic pediatric follow-up is essential for infants born following pregnancies with unexplained polyhydramnios.
  • Early identification and management of potential complications are critical.

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