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Lacunar infarct or deep intracerebral hemorrhage: who gets which? The Northern Manhattan Study
Daniel L Labovitz1, Bernadette Boden-Albala, W Allen Hauser
1Department of Neurology, New York University School of Medicine, New York, NY 10016, USA. daniel.labovitz@med.nyu.edu
Insights
Older age, diabetes, and high cholesterol distinguish lacunar infarcts (LACs) from deep intracerebral hemorrhages (DICHs). These findings aid in understanding the differing pathologies of these related cerebrovascular events.
Area of Science:
- Neurology
- Cerebrovascular Diseases
- Epidemiology
Background:
- Lacunar infarcts (LACs) and deep intracerebral hemorrhages (DICHs) share anatomical locations and potential underlying pathologies.
- The reasons for presentation as LAC versus DICH remain unclear.
Purpose of the Study:
- To compare patient characteristics between LAC and DICH cases.
- To identify factors differentiating LAC from DICH.
Main Methods:
- Utilized data from a population-based incidence study.
- Conducted multivariate analysis comparing LAC and DICH cohorts.
Main Results:
- LAC cases were significantly older than DICH cases.
- Diabetes mellitus was more prevalent in LAC cases.
- Higher cholesterol levels were observed in LAC cases compared to DICH cases.
Conclusions:
- Age, diabetes, and cholesterol levels are significant factors associated with LAC presentation over DICH.
- These findings contribute to understanding the distinct risk profiles and potential etiologies of LAC and DICH.
Abstract:
Lacunar infarcts (LACs) and deep intracerebral hemorrhages (DICHs) occur in the same structures and may result from the same pathology. It is unclear why one patient has an LAC while another has DICH. We compared LAC to DICH cases derived from a population-based incidence study. In multivariate analysis, LAC cases were significantly older, more likely to have diabetes, and had higher cholesterol than DICH cases.
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