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Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
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Updated: Jul 16, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
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A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

HCV: the Indian scenario.

Ashis Mukhopadhya1

  • 1Department of Gastrointestinal Sciences, Christian Medical College, Vellore, TN 632004, India. ashis@cmcvellore.ac.in

Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
|February 22, 2007
PubMed
Summary

Hepatitis C virus (HCV) infection is a growing global concern, particularly in India. This review examines HCV prevalence, risk factors, and genotypes within India, highlighting its public health significance.

Area of Science:

  • Hepatology
  • Virology
  • Public Health

Background:

  • Hepatitis C is a significant global health issue, affecting 170 million worldwide.
  • It is an emerging infection in India, posing a major public health challenge.
  • The precise scope and risk factors for Hepatitis C in India remain unclear.

Purpose of the Study:

  • To review the prevalence of Hepatitis C across different Indian population groups.
  • To explore the association between Hepatitis C infection and liver disease in India.
  • To identify the predominant Hepatitis C genotypes circulating in India.

Main Methods:

  • Systematic literature review of Hepatitis C prevalence studies in India.
  • Analysis of data on Hepatitis C and liver disease co-occurrence.

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Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors

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Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
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  • Genotyping data compilation from relevant Indian studies.
  • Main Results:

    • Hepatitis C prevalence varies across different Indian demographics.
    • A clear association exists between Hepatitis C infection and liver disease burden in India.
    • Specific Hepatitis C genotypes are prevalent in the Indian population.

    Conclusions:

    • Hepatitis C represents a substantial and growing public health concern in India.
    • Further research is needed to fully define prevalence and risk factors.
    • Understanding genotypes is crucial for effective treatment and control strategies in India.