Related Experiment Video
Updated: Jul 16, 2026
10:26
Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
[Experimental study of root dentine permeability for medicines]
Stomatologiia
|February 22, 2007
Summary
Even modern root canal treatments can leave persistent infections. This study found that tooth root dentine is most permeable in the cervical third, affecting treatment efficacy.
Area of Science:
- Endodontics
- Microbiology
- Dental Materials Science
Context:
- Contemporary endodontic treatments may not fully eradicate chronic periodontium infections.
- Filled teeth can harbor residual infection despite appearing healthy clinically and radiographically.
Purpose:
- To investigate the permeability of tooth root dentine to medications and microorganisms.
- To assess the efficacy of iodine-electrophoresis in evaluating dentine permeability and microbial inhibition.
Summary:
- Dentine permeability was studied using a colorant introduced via iodine-electrophoresis.
- Medication penetration from the root canal through tooth hard tissues was observed.
- The inhibition of microbial growth in a nutrient medium was also assessed.
- Maximum dentine permeability was identified in the cervical third of the tooth root.
Impact:
- Findings highlight the cervical third of the root as a critical area for potential persistent infection.
- Results may inform the development of improved endodontic treatment strategies to enhance disinfection.
- Understanding dentine permeability is crucial for optimizing medication delivery and preventing post-treatment infections.
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