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Combinatorial RNAi: a winning strategy for the race against evolving targets?

Dirk Grimm1, Mark A Kay

  • 1Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|February 22, 2007
PubMed
Summary

Combinatorial RNAi (coRNAi) strategies combine RNA interference with other gene silencing methods to combat viral resistance and genetic diseases. This approach offers therapeutic potential but requires careful consideration of associated risks for clinical application.

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