Automated identification of minimal myocardial motion for improved image quality on MR angiography at 3 T

Ali Ustun1, Milind Desai, Khaled Z Abd-Elmoniem

  • 1Department of Radiology, Johns Hopkins University Medical School, JHOC 4223, 601 N Caroline St., Baltimore, MD 21287, USA.

Abstract

Insights

FREEZE, an automated tool, improves coronary magnetic resonance angiography (MRA) image quality by identifying minimal myocardial motion. This enhances vessel sharpness and signal-to-noise ratio, making MRA more reliable and easier to perform.

Area of Science:

  • Cardiovascular Imaging
  • Medical Physics
  • Magnetic Resonance Imaging

Background:

  • Minimizing myocardial motion is crucial for high-quality coronary magnetic resonance angiography (MRA).
  • Accurate identification of the quiescent cardiac phase is essential for optimal image acquisition.
  • Existing methods may be operator-dependent and time-consuming.

Purpose of the Study:

  • To evaluate the effectiveness of FREEZE, a custom automated tool, in identifying minimal myocardial motion.
  • To assess the impact of FREEZE on coronary MRA image quality in a phantom and in healthy volunteers.
  • To determine if FREEZE improves objective measurements and subjective image quality assessments.

Main Methods:

  • FREEZE was tested on a moving phantom at 1.5 T and 10 healthy adults at 3 T.
  • Coronary MRA was performed using the period of minimal myocardial motion identified by FREEZE.
  • Objective metrics (dimension measurements, sharpness, SNR, CNR) and subjective image quality were analyzed.

Main Results:

  • Dimension measurements in the moving phantom approached static phantom accuracy with FREEZE.
  • Vessel sharpness, SNR, and CNR significantly improved in vitro during FREEZE-guided MRA (p < 0.05).
  • Consensus review confirmed significant improvements in overall image quality using FREEZE.

Conclusions:

  • The FREEZE tool effectively identifies the period of minimal myocardial motion for coronary MRA.
  • Utilizing FREEZE significantly enhances coronary MRA image quality, including vessel sharpness and SNR.
  • FREEZE improves ease of use and reduces operator dependence in coronary MRA acquisition.