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Updated: Jul 16, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

Recurrent miscarriage: psychological and relational consequences for couples.

Fátima Serrano¹, Maria Luisa Lima

¹Maternidade Alfredo da Costa, Lisboa, Portugal.

Psychology and Psychotherapy

|February 23, 2007

Summary

Recurrent miscarriage impacts couples, causing grief and sexual changes. While men grieve less intensely than women, communication quality affects female grief, and sex life quality affects male grief.

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Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis

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Published on: October 13, 2023

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Last Updated: Jul 16, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis

Published on: October 13, 2023

Area of Science:

Reproductive Medicine
Psychology
Sociology

Background:

Recurrent miscarriage (RM) is a traumatic reproductive event.
RM's impact on couple sexuality and gendered grief responses is understudied.
Existing research links RM to depression, anxiety, and lowered self-esteem.

Purpose of the Study:

To investigate the effects of recurrent pregnancy loss on couple relationships.
To explore gender differences in attitudes and grief intensity following RM.
To understand the impact of RM on couple sexuality.

Main Methods:

30 couples with at least 3 RM events participated.
Individual questionnaires assessed grief, relationship quality, and sexual changes.
Validated scales included the Impact of Events Scale and Perinatal Grief Scale.

Main Results:

Men grieve RM, but less intensely than women.
The couple's relationship quality was not adversely affected by RM.
Couples reported significant sexual changes post-RM.
Women's grief correlated with communication quality; men's grief correlated with sexual quality.

Conclusions:

RM elicits distinct gendered grief responses and impacts sexual intimacy.
Communication and sexual quality are key factors influencing grief in women and men, respectively.
Further research should address RM's psychosocial and sexual sequelae.