Related Experiment Video
Updated: Jul 16, 2026

07:17
Production and Detection of Reactive Oxygen Species (ROS) in Cancers
Published on: November 21, 2011
[Effect of ronkoleukin on nitric oxide and lipid peroxidation indices in hepatocarcinogenesis]
Likars'Ka Sprava
|February 23, 2007
Abstract:
Hepatocarcinogenesis induced by DENA lead to increase in NO2 level, decrease in L-Arginin and Malonic Di-aldehyde (MDA) levels. The use of doksorubicyn slightly increases L-Arginin level in blood serum in mice without affecting considerably nitrite levels. Doksorubicin application in combination with ronkoleukin enables profound consumption of L-Arginin, increases nitrite levels and MDA. It is likely connected with increased formation of peroxynitrite which negatively affects tumor cells.

