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Updated: Jul 16, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Evaluating cardiac sources of embolic stroke with MRI
Asu Rustemli1, Tandeep K Bhatti, Steven D Wolff
1Division of Cardiology, Department of Medicine, Columbia University, New York, New York, USA.
Insights
Diagnosing cardioembolic stroke involves cardiac imaging. Echocardiography and cardiac magnetic resonance (CMR) imaging are compared for detecting stroke causes like thrombus and patent foramen ovale.
Area of Science:
- Cardiology
- Neurology
- Radiology
Background:
- Stroke evaluation requires identifying etiology for tailored therapy.
- Current diagnostics include brain, head/neck artery, aorta, and heart imaging.
- Traditional cardiac imaging includes echocardiography (TTE/TEE).
Purpose of the Study:
- To review the advantages and limitations of echocardiography and cardiac magnetic resonance (CMR) imaging.
- To compare these modalities in diagnosing cardioembolic stroke.
- To discuss their current clinical practice roles.
Main Methods:
- Review of echocardiography (TTE/TEE) and cardiac magnetic resonance (CMR) imaging.
- Focus on diagnosing common cardioembolic stroke etiologies.
- Comparison of diagnostic capabilities.
Main Results:
- Echocardiography is a cornerstone of cardiac imaging.
- CMR increasingly assesses key cardioembolic stroke sources: left atrial/appendage thrombus, left ventricular thrombus, aortic atheroma, cardiac masses, and patent foramen ovale.
- Both modalities have distinct advantages and limitations.
Conclusions:
- Both echocardiography and CMR are vital in evaluating patients with suspected embolic stroke.
- The choice of imaging modality depends on specific clinical scenarios and suspected etiologies.
- Further understanding of their roles aids in optimizing patient management.
Abstract:
The evaluation of patients with stroke includes identifying its etiology in order to appropriately tailor therapy. Currently, the diagnostic work-up includes imaging of the brain, the arteries of the head and neck, the aorta, and the heart. Traditional methods of imaging include magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA), duplex ultrasound, and transthoracic echocardiography (TTE) and/or transesophageal echocardiography (TEE). While echocardiography remains a cornerstone in the field of cardiac imaging, MRI is increasingly able to assess for the most common causes of cardioembolic stroke such as left atrial/left atrial appendage thrombus, left ventricular thrombus, aortic atheroma, cardiac masses and patent foramen ovale. This review will focus on the advantages and limitations of echocardiography and cardiac magnetic resonance (CMR) imaging in diagnosing patients suspected of having an embolic stroke and the role these modalities play in clinical practice today.
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