The diagnosis of Paget's disease of bone

Paget's disease of the bone is a common disorder and usually presents no diagnostic difficulty. However, atypical cases may cause problems in diagnosis, particularly in younger patients, and this paper describes some of the more unusual modes of presentation mainly related to the osteolytic phase and to accentuation of normal anatomical features. The role of various imaging techniques is discussed, emphasizing that recognition of the plain radiographic changes of Paget's disease remains the key to diagnosis in most cases.