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Related Experiment Video

Updated: Jul 16, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

CyberKnife radiosurgery for spinal neoplasms.

Peter C Gerszten1, Steven A Burton, Cihat Ozhasoglu

  • 1Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pa., USA.

Progress in Neurological Surgery
|February 24, 2007
PubMed
Summary

Frameless image-guided stereotactic radiosurgery offers a safe and feasible treatment for spinal lesions. This advanced technique provides precise radiation delivery, enabling outpatient treatment with rapid recovery and good symptomatic response.

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Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Medical Physics

Background:

  • Stereotactic radiosurgery (SRS) is established for intracranial lesions.
  • Spinal SRS has been limited by immobilization and localization challenges.
  • Conventional radiotherapy lacks precision for spinal cord radiosensitivity.

Purpose of the Study:

  • To evaluate the feasibility and safety of frameless image-guided SRS for spinal lesions.
  • To introduce the CyberKnife system for spinal radiosurgery.
  • To highlight the benefits of this technique for spinal lesion treatment.

Main Methods:

  • Utilized the CyberKnife, an image-guided, frameless SRS system.
  • Employed real-time imaging tracking with 1mm spatial accuracy.

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Last Updated: Jul 16, 2026

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  • Tracked cervical lesions via skull landmarks and lower spine lesions via gold fiducial markers.

    • Main Results:

    • Frameless image-guided spinal SRS is feasible and safe.
    • The CyberKnife system enables precise radiosurgical treatment of spinal lesions.
    • Potential benefits include short outpatient treatment times and rapid recovery.

    Conclusions:

    • Spinal stereotactic radiosurgery using a frameless image-guided system is a viable therapeutic option.
    • This technique is suitable for various spinal lesions, including those not amenable to surgery or in previously irradiated sites.
    • Offers a successful modality as primary treatment, adjunct to surgery, or for medically inoperable patients.