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Portable Paper-Based Immunoassay Combined with Smartphone Application for Colorimetric and Quantitative Detection of Dengue NS1 Antigen
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Portable Paper-Based Immunoassay Combined with Smartphone Application for Colorimetric and Quantitative Detection of Dengue NS1 Antigen

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CRM1-dependent nuclear export of dengue virus type 2 NS5

Melinda J Pryor1, Stephen M Rawlinson, Peter J Wright

  • 1Department of Biochemistry and Molecular Biology, Monash University, Victoria 3800, Australia.

Novartis Foundation Symposium
|February 27, 2007
PubMed

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Nuclear Export of mRNA

Before mRNAs are exported to the cytoplasm, it is crucial to check each mRNA for structural and functional integrity. Eukaryotic cells use several different mechanisms, collectively known as mRNA surveillance, to look for irregularities in mRNAs. Irregular or aberrant mRNA are rapidly degraded by various enzymes. If a defective mRNA escapes the surveillance, it would be translated into a protein which would either be non-functional or not function properly. One of the primary irregularities in...
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