Related Experiment Video

Updated: Jul 16, 2026

Multimodal Quantitative Phase Imaging with Digital Holographic Microscopy Accurately Assesses Intestinal Inflammation and Epithelial Wound Healing
07:38

Multimodal Quantitative Phase Imaging with Digital Holographic Microscopy Accurately Assesses Intestinal Inflammation and Epithelial Wound Healing

Published on: September 13, 2016

[New drugs; omalizumab]

A F Cohen1, E A Dubois, H van Bronswijk

  • 1Centre for Human Drug Research, Leiden. ac@chdr.nl

Nederlands Tijdschrift Voor Geneeskunde
|February 27, 2007
PubMed

Omalizumab is a humanised monoclonal antibody that binds to circulating IgE, inhibiting its binding to the surface of mast cells and basophilic granulocytes. This prevents the release of pro-inflammatory mediators that produce an allergic response. This targeted mechanism of action provides a novel therapeutic approach for the treatment of patients with severe persistent, therapy-resistant allergic asthma. Omalizumab is administered subcutaneously in addition to other anti-asthma therapy. Until recently, the most important side effects are skin reactions at the site of administration and headache. Prospective data on additional long-term side effects are still being collected.

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