Intraoperative diclofenac for post-adenoidectomy analgesia in small children

Area of Science:

• Pediatric Anesthesiology
• Pain Management
• Pharmacology

Background:

• Adenoidectomy is a common pediatric surgical procedure.
• Post-operative pain is a significant concern following adenoidectomy.
• Effective pain management is crucial for patient recovery and well-being.

Purpose of the Study:

• To evaluate the analgesic efficacy of intra-operative intravenous diclofenac in children undergoing adenoidectomy.
• To compare pain levels in children receiving diclofenac versus placebo.
• To assess the safety and effectiveness of diclofenac for immediate post-operative pain relief.

Main Methods:

• A randomized, double-blind, placebo-controlled study involving 150 children aged 1-7 years.
• Standard anesthetic techniques were employed, with all children receiving diazepam premedication.
• Diclofenac (1 mg/kg IV followed by 2-hour infusion) or placebo was administered intra-operatively.

Main Results:

• Children in the diclofenac group experienced significantly lower pain scores at rest and during swallowing in the recovery room.
• Vital signs were continuously monitored, indicating no adverse events related to diclofenac administration.
• Statistical analysis using Student's t-test confirmed the analgesic effect of diclofenac.

Conclusions:

• Intra-operative intravenous diclofenac provides effective analgesia in the immediate post-operative period after adenoidectomy.
• Diclofenac is a safe and recommended option for pain management in young children undergoing this procedure.
• Optimizing post-adenoidectomy pain control can improve patient outcomes and recovery.