Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interframe clutter filtering for high frequency flow imaging.

Andrew Needles1, David E Goertz, Alison M Cheung

  • 1Sunnybrook Health Sciences Centre, Toronto, Canada. aneedles@swri.ca

Ultrasound in Medicine & Biology
|February 27, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultra-High Frequency Ultrasound Imaging and Quantification of Microvascular Flow in Xenograft Renal Cell Carcinoma in an Avian Chorioallantoic Membrane Model.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2026
Same author

Histotripsy of Blood Clots within Hollow Cylindrical Transducers for Aspiration Thrombectomy Applications.

Ultrasound in medicine & biology·2026
Same author

Heterogeneity and immune microenvironment of early invasive estrogen receptor-positive breast cancer reveal an immune-rich subset.

NPJ breast cancer·2026
Same author

Self-Sensing with Hollow Cylindrical Transducers for Histotripsy-Enhanced Aspiration Mechanical Thrombectomy Applications.

Sensors (Basel, Switzerland)·2025
Same author

Extending the Transmit and Receive Bandwidths of Dual-Frequency Transducers Toward Clinical Acoustic Angiography: In Vitro and In Vivo Studies.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2025
Same author

Intra-tumoral spatial heterogeneity in breast cancer quantified using high-dimensional protein multiplexing and single cell phenotyping.

Breast cancer research : BCR·2025

Interframe clutter filtering enhances high frequency (HF) microvascular imaging performance at high frame rates. This technique improves flow data accuracy, enabling better visualization of blood flow in small vessels and tumors.

Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Fluid Dynamics

Background:

  • High frame rate (HFR) ultrasound imaging is crucial for microvascular visualization.
  • Traditional clutter filtering methods struggle with spectral broadening at HFR.
  • Interframe filtering offers a potential solution by leveraging temporal signal correlations.

Purpose of the Study:

  • To investigate the efficacy of interframe clutter filtering for HFR microvascular imaging.
  • To assess the performance improvement in Power Doppler (PD) and Color Flow (CF) imaging.
  • To validate the technique in both in vitro and in vivo settings.

Main Methods:

  • Development and application of an interframe clutter filtering algorithm for HF flow imaging.
  • In vitro experiments using a flow phantom with controlled velocities (0.5-70.0 mm/s).

Related Experiment Videos

  • Acquisition of PD and CF imaging data at slow (0.25 fps) and fast (20 fps) frame rates.
  • In vivo validation in a human finger's microvasculature and murine tumor models.

    • Main Results:

    • Interframe filtered HFR data (20 fps) showed comparable velocity and mean Doppler power to slower acquisitions (0.25 fps).
    • Successful detection of blood flow (2-3 mm/s) in a 500 micrometer human finger vessel.
    • Demonstrated feasibility of HFR PD and CF imaging in experimental murine tumors.

    Conclusions:

    • Interframe clutter filtering significantly improves HFR microvascular imaging performance.
    • The technique maintains accuracy comparable to slower frame rates, overcoming spectral broadening limitations.
    • This method enables advanced HF ultrasound applications in clinical and research settings.