Related Experiment Video
Updated: Jul 16, 2026
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
[Ocular pulse amplitude: a new biometrical parameter for the diagnose of glaucoma?]
T Romppainen1, C Kniestedt, L M Bachmann
1Augenklinik, Universitätsspital Zürich, Frauenklinikstrasse 24, 8091 Zürich, Schweiz. timosamuel.romppainen@usz.ch
Background:
Dynamic contour tonometry (DCT) enables accurate transcorneal measurements of the intraocular pressure and ocular pulse amplitude (OPA). In this study, we investigated whether this new biometrical parameter can characterize different glaucoma types and serve as a helpful tool in the diagnosis and therapy of the disease.
Patients And Methods:
A total of 441 eyes of 222 patients were included. Pressure measurements were performed with contour and applanation tonometry.
Results:
Mean OPA was 3.1+/-1.4 mmHg. Eyes with ocular hypertension showed significantly higher OPA values (3.6+/-1.3 mmHg) than healthy eyes (3.1+/-1.4 mmHg) and eyes with low-tension glaucoma (2.9+/-1.4 mmHg). After trabeculectomy, the values were significantly lower (2.4+/-1.3 mmHg) than in healthy eyes.
Conclusion:
The size of the OPA seems to be characteristic for different types of glaucoma and directly dependent on intraocular pressure levels. Further investigation is indicated to clarify its diagnostic usefulness.
Related Concept Videos
01:25Glaucoma: Overview
01:17Pulse amplitude and quality
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
01:27Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:28Angle Closure Glaucoma: Treatment