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Published on: October 12, 2014
Packing efficacy of hydrocoil embolic system: in vitro study using ruptured aneurysm model
Kyoichi Watanabe1, Kenji Sugiu, Koji Tokunaga
1Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama 700-8558, Japan.
Neurosurgical Review
|February 27, 2007
Summary
The HydroCoil Embolic System (HES) shows improved packing efficacy for cerebral aneurysms compared to bare platinum coils. HES offers a higher initial occlusion rate and appears safe for endovascular embolization.
Area of Science:
- Neurosurgery
- Interventional Radiology
- Biomaterials
Background:
- Endovascular coil embolization is a common treatment for cerebral aneurysms.
- Coil compaction and aneurysm recanalization remain challenges after embolization.
- The HydroCoil Embolic System (HES) was developed to enhance packing density.
Purpose of the Study:
- To evaluate the packing efficacy of the HydroCoil Embolic System (HES).
- To compare HES with bare platinum coils in a simulated ruptured cerebral aneurysm model.
Main Methods:
- A silicone model of a ruptured cerebral aneurysm was used.
- The model was connected to a pulsatile flow pump.
- Embolization was performed using framing coils followed by either hydro coils (n=3) or bare platinum coils (n=3).
Main Results:
- Continuous outflow cessation occurred in 2 out of 3 cases with hydro coils.
- Outflow decreased but did not stop in all cases with bare platinum coils.
- Hydro coils demonstrated a higher initial occlusion rate and potential direct sealing of the rupture site.
Conclusions:
- The HydroCoil Embolic System (HES) appears to improve packing efficacy in endovascular coil embolization.
- HES showed a higher initial occlusion rate in the tested model.
- The device is considered safe and feasible, with a low risk of over-expansion.
